Enantioselective Total Synthesis of (-)-Colchicine, (+)-Demecolcinone and Metacolchicine

    Chen, B.; Liu, X.; Hu, Y.-J.; Zhang, D.-M.; Deng, L.J.; Lu, J.Y.; Min, L.; Ye, W.-C.; Li, C.-C.*

    Chem. Sci.2017in press[doi]

    


    Toward the Total Synthesis of Eurifoloid A

    Liu, X.; Liu, J.Y.; Zhao, J.*; Li, S.*Li, C.-C.*

    Org. Lett.2017in press [doi]

   


    Synthetic Study toward the Total Synthesis of Solanoeclepin A

    Liu, G.; Han, J.-C.; Li, C.-C.*

    Tetrahedron2017, Early View. [doi]
         

    Recent Progress toward the Total Synthesis of Humulanolides

    Han, J.-C.; Liu, X.; Zhao, J.; Li, S.; Li, C.-C.*

    Tetrahedron2017, Early View. [doi]
         


    Catalytic Enantioselective Total Synthesis of Hypocrolide A

    Qiao, C.; Zhang, W.; Han, J.; Li, C.-C.*

    Org. Lett.201618, 4932. [doi]

    • Top 10 Most Accessed Article in 10/2016.
 
     


     Ruthenium-Catalyzed Metathesis Cascade Reactions in Natural Products Synthesis

    Han, J.; Li, C.-C.*

    The Chemial Record.2016, Early View. [doi]
    
     •  An invited Account article.


    Collective Synthesis of Natural Products Using Metathesis Cascade Reactions

    Han, J.; Li, C.-C.*

    Synlett., 2015, 26, 1289. [doi]
    
     •  An invited Account article.
     



    Type II Intramolecular [5+2] Cycloaddition: Facile Synthesis of Highly Functionalized Bridged            Ring Systems

Mei, G.; Liu, X.; Qiao, C.; Chen, W.; Li, C.-C.*

Angew. Chem. Int. Ed.201554, 1745. [doi]

• Highlighted in SUSTC NEWS2014.

• Highlighted in Angew Cover2015.


     Collective Synthesis of Humulanolides Using a Metathesis Cascade Reaction

     Han, J.; Li, F.; Li, C.-C.*

     J. Am. Chem. Soc.2014, 136, 13610. [doi]


       Dearomative Indole [5+2] Cycloaddition Reactions: Stereoselective Synthesis of Highly 

      Functionalized Cyclohepta[b]indoles

      Mei, G.; Yuan, H.; Gu, Y.; Chen, W.; Chung, L.; Li, C.-C.*

      Angew. Chem. Int. Ed., 2014, 53, 11051. [doi]


          Total Synthesis of Aplykurodinone-1

         Liu,G.; Mei, G.; Chen, R.; Yuan, H.; Yang, Z.*; Li, C.-C.*

         Org. Lett., 2014, 16, 4380. [doi]

          • Top 10 Most Accessed Article in 08/2014.


  Collective Synthesis of Cladiellins Based on the Gold-Catalyzed Cascade Reaction of 1,7-Diynes

     Yue, G.; Zhang, Y.; Fang, L.; Li, C.-C.; Luo, T.*; Yang, Z.*

  Angew. Chem. Int. Ed., 2014, 53, 1837. [doi]


       Development of an Expedient Intramolecular Pauson-Khand Reaction Approach to                            Stereoselectively Construct the trans-Decalin with C1 Quaternary Chiral Center

  Shi, L.; Shen, H.; Fang, L.; Huang, J.; Li, C.-C.*; Yang, Z.*

  Chem. Commun., 2013, 49, 8806. [doi]


  Asymmetric Total Synthesis of (+)-Fusarisetin A via the Intramolecular Pauson-Khand    Reaction

  Huang, J.; Fang, L.; Long, R.; Shi, L.; Shen, H.;Li, C.-C.*; Yang, Z.*

  Org. Lett., 2013, 15, 4018. [doi]

  • Top10 Most Accessed Article in 07/2013.

  • Highlighted in Synfacts, 2014, 10, 8.


  Asymmetric Total Synthesis of Caribenol A via an Intramolecular Diels–Alder        Reaction

  Han, J.; Liu, L.; Chang, Y.; Yue, G.; Guo, J.; Zhou, L.; Li, C.-C. *; Yang, Z.*

  J. Org. Chem., 2013, 78, 5492. [doi]

  • Highlighted in Synfacts, 2013, 9, 809.

  • Highlighted in Org. Chem. Highlights, December, 2013.


  Asymmetric, Protecting-Group-Free Total Synthesis of (+)-Caribenol A

  Han, J.; Liu, L.; Li, C.-C. *; Yang, Z.*

  Chem. Asian J., 2013, 8, 1972. [doi]


  Reverse Regioselectivity in the Palladium(II) Thiourea Catalyzed Intermolecular Pauson–Khand          Reaction

  Wu, N.; Deng, L.; Liu, L.; Liu, Q.; Li, C.-C.*; Yang, Z.*

  Chem. Asian J., 2013, 8, 65. [doi]


  Stereoselective Total Syntheses of (−)-Flueggine A and (+)-Virosaine B

  Wei, H.; Qiao, C.; Liu, G.; Yang, Z.*; Li, C.-C.*

  Angew. Chem. Int. Ed., 2013, 52, 620. [doi]

  • Chosen as “Hot Paper” by the Editors.

  • Top 3 Most Accessed Article in 11/2012.

  • Highlighted in PKUSZ NEWS, 2012.

  • Highlighted in Chemistry World, January, 2013.

  • Highlighted in Synfacts, 2013, 9, 237 (“Synfact of the Month”).


  Synthesizing the Tetracyclic Core of Nanolobatolide

  Chang, L.; Jiang, H.; Fu, J.; Liu, B.; Li, C.-C.*; Yang, Z.*

  J. Org. Chem., 2012, 77, 3609. [doi]


  Total Synthesis of (±)-Pentalenolactone A Methyl Ester

  Liu, Q.; Yue, G.; Wu, N.; Lin, G.; Li, Y.; Quan, J.; Li, C.-C.*; Wang, G.*; Yang, Z.*

  Angew. Chem. Int. Ed., 2012, 51, 12072. [doi]

  • Top 10 Most Accessed Article in 10/2012.

  • Highlighted in Chin. J. Org. Chem., January, 2013.

  • Highlighted in Chemistry World, November, 2012.


  InCl3-mediated intramolecular Friedel-Crafts-type cyclization and its application to construct the          [6-7-5-6] tetracyclic scaffold of liphagal

  Jiang, H.; Tian, L.; Li, Z.; Liu, Q.; Li, C.-C.*; Yao, X.* ; Yang, Z.*

  Science China Chemistry., 2012, 50, 36. [doi]


  A Concise Approach for the Total Synthesis of Pseudolaric acid A

  Xu, T.; Li, C.-C.*; Yang, Z.*

  Org. Lett., 2011, 13, 2630. [doi]

  • “Highlight syntheses” in Annu. Rep. Prog. Chem., Sect. B: Org. Chem.2012.


  Total Syntheses of Drimane-Type Sesquiterpenoids Enabled by a Gold-Catalyzed Tandem                   Reaction

  Shi, H.; Fang, L.; Tan, C.; Shi, L.; Zhang, W.; Li, C.-C.*; Luo, T.*; Yang, Z.*

  J. Am. Chem. Soc., 2011, 133, 14944. [doi]

  • Highlighted in Org. Chem. Highlights, August, 2012.


  Fomal Synthesis of Cortistatins

  Fang, L.; Chen, Y.; Huang, J.; Liu, L.; Li, C.-C.*; Yang, Z* .

  J. Org. Chem., 2011, 76, 2479. [doi]


  A Thiourea-Oxazoline Library with Axial Chirality: Ligand Synthesis and Studies of the                      Palladium-Catalyzed EnantioselectiveBis(methoxycarbonylation) of Terminal Olefins

  Gao, Y.; Chang, L.; Shi, H.; Liang, B.; Wongkhan, K.; Chaiyaveij, D.; Batsanov, A.; Marder,           T.; Li,C.-C.*; Yang, Z.*; Huang, Y*.

  Adv. Synth.Catal., 2010, 352, 1955. [doi]


  Total Synthesis of (±) Maoecrystal V

  Gong, J.; Lin, G.; Sun, W.; Li, C.-C.*; Yang, Z.*

  J. Am. Chem. Soc., 2010, 132, 16745. [doi]

  • Top3 Most Accessed Article in J. Am. Chem. Soc. of 2010.

  • Highlighted in Nature, December, 2010.

  • Highlighted in Chemistry World, December, 2010.

  • Highlighted in Synfacts, 2011, 3, 239 (“Synfact of the Month”).

  • Highlighted in Org. Chem. Highlights, June, 2011.


  Asymmetric Total Synthesis of Caribenol A

  Liu, L.; Han, J.; Yue, G.; Li, C.-C.*; Yang, Z.*

  J. Am. Chem. Soc., 2010, 132, 13608. [doi]

  • Top5 Most Accessed Article in J. Am. Chem. Soc. of 2010.

  • Highlighted in Nature Chemistry, September, 2010.

  • Highlighted in Chin. J. Org. Chem., November, 2010.

  • “Highlight syntheses” in Annu. Rep. Prog. Chem., 2011.

  • Highlighted in Org. Chem. Highlights, August, 2011.


  Synthetic Study toward the Total Synthesis of Maoecrystal V

  Gong, J.; Lin, G.; Li, C.-C.*; Yang, Z* .

  Org. Lett., 2009, 11, 4770. [doi]


  Concise Synthesis of the CortistatinsOxatetracyclic Core through Intramolecular Diels-Alder              Reaction and OxidativeDearomatization Cyclization

  Liu, L.; Gao, Y.; Che, C.; Wu, N.; Wang, D.; Li, C-C.*; Yang, Z*.

  Chem. Commun., 2009, 662. [doi]


  Stereodivergent Synthesis of 17-a and 17-b-Aryl Steroids: Application and Biological Evaluation          of D-Ring Cortistatin Analogues

  Shi, J.; Shigehisa, H.; Guerrero, C.; Shenvi, R.; Li, C.-C.; Baran, P.

  Angew.Chem. Int. Ed., 2009, 48, 4328. [doi]


  Synthesis of (+)-Cortistatin A

  Shenvi, R.; Guerrero, C.; Shi, J.; Li, C.-C.; Baran, P.

  J. Am. Chem. Soc., 2008, 130, 7241. [doi]

  •#1 Most Accessed Article in J. Am. Chem. Soc. for all of 2008.

  • Highlighted in Nature Chemistry, May 2008.

  •Highlighted in Chemical & Engineering News, 86 (21), May 2008.

  • Highlighted in Angew. Chem. Int. Ed. 2008, 47, 9389–9391.

  •“SynFact of the Month”, Synfacts, 2008, 11, 1127.


  Synthetic Study of 1,3-Butadiene-Based IMDA Approach to Construct a [5-7-6] Tricyclic Core          and Its Application to the Total Synthesis of C8-epi-Guanacastepene O

  Li, C.-C.; Wang, C.-H.; Liang, B.; Zhang, X.-H.; Deng, L.-J.; Liang, S.; Chen, J.-H.; Wu, Y.-          D.; Yang, Z.

  J. Org. Chem., 2006, 71, 6892. [doi]


  Exploring Expedient IMDA Reaction Approach to Construct the anacastepenes’s Core

  Li, C.-C.; Liang, S.; Zhang, X.-H.; Xie, Z.-X.; Chen, J.-H.; Wu, Y.-D.; Yang, Z.

  Org. Lett., 2005, 7, 3709. [doi]


  Total Synthesis of Wedelolactone

  Li, C. C.; Xie, Z. X.; Zhang, Y. D.; Chen, J. H.; Yang, Z.

  J. Org. Chem., 2003, 68, 8500. [doi]


  Compounding Method of Maoecrystal

  Yang, Z.; Li, C.-C.; Gong, J.

  Chinese Patent: CN101974013.


  Total Synthesis of Flueggine A, Norsecurinine, Virosaine B and Allonorsecurinine

  Li, C.-C.; Yang, Z.; Wei, H.

  Chinese Patent: CN103059034A.


  Compounding Method of Cladiellin and Pachycladin D

  Yue, G.; Zhang, Y.; Li, C.-C.; Luo, T.;Yang, Z.

  Chinese Patent: CN201310400640.


  Total Synthesis of Antrocin

  Shi, H.; Shi, L.; Zhang, W.; Li, C.-C.; Yang, Z.

  Chinese Patent: CN201100664899.


  Method for chemical synthesis of antrocin and use thereof for suppressing non-small cell lung            cancer

  Yang, Z.; Tzeng, Y.; Li, C.-C.; Luo, T.; Shi, H.; Yeh, C.;

  Patent: WO2013020285 A1.


  Synthesis of (+) Corstistatin A and Related Compounds

  Shenvi, R. A.; Guerrero, C. A.; Shi, J.; Li, C. C.; Baran, P. S.

  Wipo Patent: WO/2009/137335.


  Stereoselective Synthesis of 17-α and 17-β-Aryl Steroidal Compounds

  Shi, J.; Shigehisa, H.; Guerrero, C. A.; Shenvi, R. A.; Li, C.-C.; Baran, P. S.

  International Patent Application No. PCT/US09/42404.


  Total Synthesis of Wedelolactone and Application

  Li, C. C.; Xie, Z. X.; Chen, J. H.; Yang, Z.

  Chinese Patent: CN031465846.

 

 

 

 


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